The Integrated School of Science celebrated its 16th Foundation Day Celebration last December 17-21, 2020. The theme for the celebration was "Innovating Learning". According to Atty. Felson M. Dalaguete, CPA, the school president, the theme focuses on the start of the school's digital transformation journey. This year the school has partnered with a industry-leaders in the world of digitalization.

There were a lot of activities during the week long celebration, the highlight of which is the Mr. and Ms. iS 2019.